The first region that will be completely set in March Madness is the Midwest Regional. Texas A&M – Corpus Christi and Texas Southern will meet in the opening First Four game with the winner going on to play No. 1 seed Kansas in Fort Worth. It will be a unique situation for the No. 1 seed Jayhawks, as they will be playing in the home state of their opponent despite being the top seed in the region. Still, Kansas is the favorite to win the Midwest Region per the March Madness betting odds.
Midwest Region Betting Odds at BetOnline
Kansas +230
Auburn +250
Iowa +325
Wisconsin +1000
LSU +1000
USC +2200
San Diego State +2200
Miami (FL) +2500
Providence +2800
Creighton +3300
Iowa State +5000
Richmond +6600
South Dakota State +10000
Colgate +20000
Texas A&M – Corpus Christi +20000
Texas Southern +20000
Jacksonville State +25000
Kansas is the best bet to win the Midwest Region. The Jayhawks are currently a steal at +230 to make the Final Four. They were able to win the Big 12 Conference Tournament and topped the Big 12 in the regular season, and they have the sixth best offense in the country according to Ken Pomeroy. Ochai Agbaji is an extremely talented senior that is hitting over 40% of his threes while averaging 19.7 PPG, and Christian Braun, Jalen Wilson, and David McCormack are effective shooters too. This is the weakest region in the NCAA Tournament, and Kansas should take full advantage.
Auburn has the best player in this region. Jabari Smith is likely to be the No. 1 pick in the 2022 NBA Draft according to the latest mock drafts. Smith has been positively compared to Rashard Lewis already, as he is a 6’10 freshman that can shoot from range. He is making 43% of his threes, and he is a superb rebounder too. Walker Kessler has been a monster down low, hitting 72.8% of his two-point field goals, and he ranks first in block rate nationally. However, the guards leave something to be desired and lack size.
The No. 3 seed and No. 4 seed in the Midwest Region aren’t good picks to make it to New Orleans. Wisconsin is ranked 34th according to Ken Pomeroy, and Providence checks in all the way back in 49th. The Badgers have a much clearer path to the Final Four, but neither they nor the Friars are good bets despite their nice prices.
There would be some value in Iowa as a No. 5 seed if they were double their price, but +325 is far too low for the Hawkeyes. They were able to win the Big Ten Tournament, but they were given a No. 5 seed for a reason. Keegan Murray has been very impressive, yet there are real concerns about how well this offense will perform against teams outside the Big Ten.
Follow our Twitter account for the latest sports news and wagering odds, and come to our Instagram for more useful betting info too.





